Hideki Aihara Selected Research

Single-Stranded DNA (DNA, Single Stranded)

5/2023	DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo.
1/2020	Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B.
12/2017	Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.
1/2017	Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
11/2015	Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hideki Aihara Research Topics

Disease

14	Neoplasms (Cancer) 05/2024 - 11/2015
5	COVID-19 05/2024 - 11/2020
3	Infections 01/2022 - 01/2018
3	Virus Diseases (Viral Diseases) 01/2022 - 12/2021
2	Superinfection 11/2020 - 09/2020
1	Tuberculosis (Tuberculoses) 11/2023
1	Hepatocellular Carcinoma (Hepatoma) 05/2023
1	Inflammation (Inflammations) 10/2022
1	Glomerulonephritis 01/2022
1	Hematuria 01/2022
1	Proteinuria 01/2022
1	Stroke (Strokes) 11/2021
1	Nervous System Diseases (Neurological Disorders) 11/2021
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Muscular Dystrophies (Muscular Dystrophy) 01/2020
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020
1	Sarcoma (Soft Tissue Sarcoma) 01/2020
1	T-Cell Leukemia (Leukemia, T Cell) 01/2020
1	Septic Shock (Toxic Shock Syndrome) 01/2018
1	Facioscapulohumeral Muscular Dystrophy 01/2016
1	Prostatic Neoplasms (Prostate Cancer) 01/2016
1	Neoplasm Metastasis (Metastasis) 11/2015
1	Acquired Immunodeficiency Syndrome (AIDS) 08/2015
1	Sexually Transmitted Diseases (Sexually Transmitted Disease) 07/2014
1	Carcinogenesis 12/2012

Drug/Important Bio-Agent (IBA)

5	Single-Stranded DNA (DNA, Single Stranded)IBA 05/2023 - 11/2015
5	DNA (Deoxyribonucleic Acid)IBA 05/2023 - 07/2014
5	EnzymesIBA 05/2023 - 11/2015
4	CytosineIBA 05/2024 - 01/2017
3	Antiviral Agents (Antivirals)IBA 05/2023 - 01/2018
3	RNA (Ribonucleic Acid)IBA 01/2022 - 12/2012
3	PoisonsIBA 02/2021 - 01/2019
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2012
3	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2016
2	Angiotensin-Converting Enzyme 2IBA 05/2024 - 01/2022
2	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 11/2021
2	Viral DNAIBA 01/2020 - 08/2015
2	Cytosine DeaminaseIBA 01/2020 - 12/2017
2	Etoposide (VP 16)FDA LinkGeneric 01/2019 - 01/2016
2	tyrosyl-DNA phosphodiesteraseIBA 01/2019 - 06/2018
2	Type II DNA Topoisomerases (Topoisomerase II)IBA 01/2019 - 06/2018
1	SARS-CoV-2 spike proteinIBA 05/2024
1	Dioctyl Sulfosuccinic Acid (DOSS)IBA 11/2023
1	Histidine KinaseIBA 11/2023
1	Heme (Haem)IBA 11/2023
1	Glutamic Acid (Glutamate)FDA Link 05/2023
1	A-Form DNA (A-DNA)IBA 05/2023
1	ChemokinesIBA 10/2022
1	Interleukin-8 (Interleukin 8)IBA 10/2022
1	3'-deoxy-3',4'-didehydro-CTPIBA 01/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	Immunoglobulins (Immunoglobulin)IBA 01/2022
1	CreatinineIBA 01/2022
1	Prednisolone (Predate)FDA LinkGeneric 01/2022
1	SteroidsIBA 01/2022
1	Viral ProteinsIBA 01/2022
1	AntibodiesIBA 12/2021
1	Amino Acids FDA Link 12/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021
1	Histones (Histone)IBA 01/2021
1	SolutionsIBA 11/2020
1	Muramidase (Lysozyme)IBA 09/2020
1	Homeodomain Proteins (Proteins, Homeobox)IBA 01/2020
1	Toll-Like Receptor 4IBA 01/2018
1	Lipid AIBA 01/2018
1	EndotoxinsIBA 01/2018
1	UracilIBA 01/2017
1	Topoisomerase II InhibitorsIBA 01/2016
1	IntegrasesIBA 07/2014
1	BuffersIBA 07/2014
1	OligonucleotidesIBA 07/2014

Therapy/Procedure

4	Therapeutics 01/2022 - 06/2018